Humnn liv ppravek side effects of actos plus metformin potahovan januvia metformin tablety, sitagliptinum, pette si pozorn tento pbalov letk, protoe obsahuje pro vs dleit daje. Ponechte si pbalov letk pro ppad, e si jej budete potebovat pest znovu. Mte-li jakkoli dal otzky, zeptejte se svho lkae, lkrnka nebo zdravotn sestry. Tento ppravek byl pedepsn januvia metformin vhradn. Nedvejte jej dn dal osob. Mohl by j ublit, a to side effects of actos plus metformin i tehdy, m-li stejn znmky onemocnn jako. Pokud se kterkoli z nedoucch ink vyskytne v zvan me, nebo pokud si vimnete jakchkoli nedoucch ink, kter nejsou uvedeny v tomto pbalovm letku, prosm, sdlte to svmu lkai nebo lkrnkovi.. Co naleznete v tomto pbalovm letku: Co je ppravek Januvia januvia metformin a k emu se pouv emu muste vnovat pozornost, ne zanete ppravek Januvia uvat. Jak se ppravek Januvia uv, mon nedouc inky, jak ppravek Januvia uchovvat. Obsah balen a dal informace.. Co je ppravek Januvia a k emu se pouv. Ppravek Januvia obsahuje livou ltku sitagliptin, kter pat do skupiny lk nazvanch inhibitory DPP-4 (inhibitory dipeptidyl peptidzy-4 kter u dosplch pacient januvia metformin s cukrovkou. Typu sniuj hladinu cukru v krvi. Typu se k tak non-inzulin dependentn diabetes mellitus neboli niddm. Tento lk pomh zvyovat hladiny inzulinu po jdle a sniuje mnostv cukru vytvenho tlem.. V lka Vm pedepsal tento lk, aby pomohl Vaemu tlu snit hladinu cukru v krvi, kterouo mte kvli cukrovce. Tento lk lze uvat januvia metformin samotn nebo v kombinaci s nktermi jinmi lky sniujcmi hladinu cukru v krvi (inzulin, metformin, derivty sulfonylmooviny nebo glitazony kter ji mete uvat na Vai cukrovku spolu s plnovanou dietou a cvienm. Co je cukrovka. Typu je onemocnn, pi nm organismus nevytv dostaten mnostv inzulinu a inzulin vytvoen organismem nepsob tak, jak. Vae tlo me vytvet i pli mnoho cukru. V takovm ppad dochz k hromadn cukru (glukzy) v krvi. Vsledkem mohou bt zvan zdravotn problmy jako onemocnn srdce, onemocnn ledvin, slepota a amputace. emu muste vnovat pozornost, ne zanete ppravek Januvia uvat. Neuvejte ppravek Januvia - jestlie jste alergick na sitagliptin nebo na kteroukoli dal sloku tohoto ppravku (uvedenou v bod 6). Upozornn a opaten, u pacient lench ppravkem Januvia byly hleny ppady zntu slinivky bin (pankreatitidy) (viz bod 4). Sdlte svmu lkai, jestlie mte nebo jste ml(a onemocnn slinivky bin (jako je znt slinivky bin (pankreatitida) lunkov kameny, zvislost na alkoholu nebo velmi vysokou hladinu triglycerid. Tyto stavy mohou zvit riziko pankreatitidy nebo jejho optovnho vskytu.
Can metformin get you high
Generic Name: metformin (met FOR min brand Names: Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet. Medically reviewed on November 9, 2017. Metformin is an oral diabetes medicine that helps control blood sugar levels. Metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Metformin is sometimes can metformin get you high used together with insulin or other medications, but it is not for treating type 1 diabetes. Important information, you can metformin get you high should not use metformin if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment). If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking metformin. This medicine may cause a serious condition called lactic acidosis. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired. Metformin side effects, get emergency medical help if you have signs of an allergic reaction to metformin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Some people develop lactic acidosis while taking this medicine. Early symptoms may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness; numb or cold feeling in your arms and legs; trouble breathing; feeling dizzy, light-headed, tired, or very weak; stomach pain, nausea with vomiting; or slow or uneven heart rate. Common metformin side effects may include: low blood sugar; nausea, upset stomach; or diarrhea. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Metformin 2000 mg a day side effects
Medically reviewed on January 15, 2018. Applies to the following metformin 2000 mg a day side effects strengths: 500 mg; 750 mg; 850 mg; 1000 mg; 500 mg/5. Usual Adult Dose for: Usual Pediatric Dose for: Additional dosage information: Usual Adult Dose for Diabetes Type. Immediate-release : Initial dose: 500 mg orally twice a day or 850 mg orally once a day. Dose titration: Increase in 500 mg weekly increments or 850 mg every 2 weeks as tolerated. Maintenance dose: 2000 mg daily in divided doses. Maximum dose: 2550 mg/day, extended-release : Initial dose: 500 to 1000 mg orally once a day. Dose titration: Increase in 500 mg weekly increments as tolerated. Maintenance dose: 2000 mg daily, maximum dose: 2500 mg daily, comments: -Metformin, if not contraindicated, is the preferred initial pharmacologic agent for treatment of type 2 diabetes mellitus. Immediate-release: Take in divided doses 2 to 3 times a day with meals; titrate slowly to minimize gastrointestinal side effects. In general, significant responses are not observed with doses less than 1500 mg/day. Extended-release: Take with the evening meal; if glycemic control is not achieved with 2000 mg once a day, may consider 1000 mg of extended-release product twice a day; if glycemic control is still not achieve, may switch to immediate-release product. Use: To improve glycemic control in adults with type 2 diabetes mellitus as an adjunct to diet and exercise. Usual Pediatric Dose for Diabetes Type 2 10 years or older : Immediate-release: Initial dose: 500 mg orally twice a day. Maintenance dose: 2000 mg daily, maximum dose: 2000 mg daily, comments: Take in divided doses 2 to 3 times a day with meals. Titrate slowly to minimize gastrointestinal side effects. Safety and effectiveness of metformin extended-release has not been established in pediatric patients less than 18 years of age. Use: To improve glycemic control in children with type 2 diabetes mellitus as an adjunct to diet and exercise. Obtain eGFR prior to initiating therapy : -eGFR less than 30 mL/min/1.73 m2: Use is contraindicated -eGFR 30 to 45 mL/min/1.73 m2: Initiating therapy is not recommended -eGFR that falls below 30 mL/min/1.73 m2 during therapy: Discontinue therapy -eGFR that falls below 45 mL/min/1.73. Iodinated contrast procedure : -For patients with eGFR between 30 and 60 mL/min/1.73 m2: Stop this drug at the time of, or before imaging procedure; re-evaluate eGFR 48 hours after procedure; restart therapy only if renal function is stable. Liver Dose Adjustments, not recommended in patients with liver impairment. Dose Adjustments -Elderly, debilitated, and malnourished patients: Titration to the maximum dose is generally not recommended. Concomitant Insulin therapy: When initiating treatment in patients currently receiving insulin, metformin should be started at 500 mg orally once a day and titrated in 500 mg increments weekly. When fasting blood glucose levels decrease to less than 120 mg/dL, consider decreasing the insulin dose by 10. Therapeutic drug monitoring/range: Steady-state plasma concentrations are achieved within 24 to 48 hours and are generally less than 1 mcg/mL. Metformin levels greater than 5 mcg/mL have been implicated as the cause of lactic acidosis. Precautions US boxed warning: lactic acidosis -Postmarketing case of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias. The onset is often subtle, accompanied only by nonspecific symptoms such metformin 2000 mg a day side effects as malaise, myalgias, respiratory distress, somnolence, and abdominal pain. Metformin-associated lactic acidosis has been characterized by elevated blood lactate levels (greater than 5 mmol/L) anion gap acidosis (without evidence of ketonuria or ketonemia an increased lactate/pyruvate ratio, and metformin plasma levels generally greater than 5 mcg/mL. Risk factors for metformin-associated lactic acidosis include with renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate age 65 years old or greater, having a radiological study with contrast, surgery, and other procedures, hypoxic states (e.g., acute congestive heart failure. If acidosis is suspected, immediately discontinue drug and hospitalize patient. Prompt hemodialysis is recommended. Safety and efficacy have not been established in patients younger than 10 years. Consult warnings section for additional precautions. Dialysis Data not available. Other Comments Administration advice : -Take orally with meals -Gastrointestinal tolerability may be improved by a slow increase in dosage; doses above 2000 mg per day may be better tolerated given 3 times a day with meals -Extended-release product: Take with evening meal; swallow whole;. Not for use in patients with type 1 diabetes or diabetic ketoacidosis. Temporarily stop treatment prior to radiologic studies utilizing iodinated contrast materials and for surgical procedures when restricted food or fluid metformin 2000 mg a day side effects intake is expected; may resume once adequate renal function is confirmed. Monitoring : Renal: Assess renal function baseline, repeat at least annually and more often as clinically indicated. Hematologic: Measure hematologic parameters annually; periodically asses Vitamin B-12 levels, especially in patients with peripheral neuropathy or anemia. Monitor glycemic control Patient advice : -Tablet shells may appear in feces, and this should not cause alarm. Inform patients about the risk of lactic acidosis, conditions that might predispose them to its occurrence, and symptoms to watch for and report. Patients should understand the signs and symptoms, risks, and treatment of low blood sugar, especially if using this drug in combination with insulin or other drugs that may lower blood sugar. Advise patient that this drug may need to be temporarily stopped if undergoing radiologic studies with intravascular iodinated contrast materials or surgical procedures that will limit food or fluid intake. Advise patients on the risks of excessive alcohol intake.
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